Vaccine, 2015-12, Vol.33 (49), p.6977-6982
2015
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- Autor(en) / Beteiligte
- Titel
- Heterosubtypic immunity to H7N9 influenza virus in isogenic guinea pigs after infection with pandemic H1N1 virus
- Ist Teil von
- Vaccine, 2015-12, Vol.33 (49), p.6977-6982
- Ort / Verlag
- Netherlands: Elsevier Ltd
- Erscheinungsjahr
- 2015
- Quelle
- Access via ScienceDirect (Elsevier)
- Beschreibungen/Notizen
- Highlights • Influenza A(H1N1)pdm09 virus infection provides heterosubtypic immunity to A(H7N9). • First time heterosubtypic immunity is demonstrated in isogenic guinea pigs. • No sterile immunity but decrease in extent and duration of virus shedding. • This model can help elucidate effect of cell mediated immunity on transmission.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0264-410XeISSN: 1873-2518DOI: 10.1016/j.vaccine.2015.08.038Titel-ID: cdi_proquest_miscellaneous_1785229974
- Format
- –
- Schlagworte
- Allergy and Immunology, Animals, Antibodies, Neutralizing - blood, Antibodies, Viral - blood, Antigens, Viral - analysis, Conflicts of interest, Cross Protection, Experiments, Female, Guinea Pigs, Heterosubtypic immunity, Immunoglobulins, Infections, Influenza, Influenza A Virus, H1N1 Subtype, Influenza A Virus, H7N9 Subtype, Influenza virus, Isogenic guinea pig, Lung - pathology, Lung - virology, Lymphocytes, Orthomyxoviridae, Orthomyxoviridae Infections - immunology, Pandemics, Respiratory tract, Swine, Swine flu, Trachea - pathology, Trachea - virology, Viruses