Details

Autor(en) / Beteiligte

• Du Toit, George
• Sayre, Peter H
• Roberts, Graham
• Sever, Michelle L
• Lawson, Kaitie
• Bahnson, Henry T
• Brough, Helen A
• Santos, Alexandra F
• Harris, Kristina M
• Radulovic, Suzana
• Basting, Monica
• Turcanu, Victor
• Plaut, Marshall
• Lack, Gideon

Titel

Effect of Avoidance on Peanut Allergy after Early Peanut Consumption

Ist Teil von

• The New England journal of medicine, 2016-04, Vol.374 (15), p.1435-1443

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• A previous trial showed that early consumption of peanuts resulted in fewer cases of allergy than did avoidance. In a follow-up study, all participants avoided peanuts from 5 to 6 years of age; those who had eaten peanuts in early life retained the ability to do so. Peanut allergy is a common and potentially life-threatening food allergy for which prevention and treatment strategies are required. 1 – 5 The Learning Early about Peanut Allergy (LEAP) trial showed that among infants at high risk for allergy, the sustained consumption of peanut, beginning in the first 11 months of life, resulted in an 81% lower rate of peanut allergy at 60 months of age than the rate among children who avoided peanuts. 6 , 7 In a study of oral immunotherapy to hen’s egg white, although children achieved unresponsiveness to an oral food challenge with egg, the majority had a reversion to egg . . .