UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 1 von 15
Datensatz exportieren als...
BibTeX
Allogeneic hematopoietic stem cell transplantation following reduced-intensity conditioning for mycosis fungoides and Sezary syndrome
Hematological oncology, 2016-03, Vol.34 (1), p.9-16
Shiratori, Souichi
Fujimoto, Katsuya
Nishimura, Machiko
Hatanaka, Kanako C.
Kosugi-Kanaya, Mizuha
Okada, Kohei
Sugita, Junichi
Shigematsu, Akio
Hashimoto, Daigo
Endo, Tomoyuki
Kondo, Takeshi
Abe, Riichiro
Hashino, Satoshi
Matsuno, Yoshihiro
Shimizu, Hiroshi
Teshima, Takanori
2016
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Shiratori, Souichi
Fujimoto, Katsuya
Nishimura, Machiko
Hatanaka, Kanako C.
Kosugi-Kanaya, Mizuha
Okada, Kohei
Sugita, Junichi
Shigematsu, Akio
Hashimoto, Daigo
Endo, Tomoyuki
Kondo, Takeshi
Abe, Riichiro
Hashino, Satoshi
Matsuno, Yoshihiro
Shimizu, Hiroshi
Teshima, Takanori
Titel
Allogeneic hematopoietic stem cell transplantation following reduced-intensity conditioning for mycosis fungoides and Sezary syndrome
Ist Teil von
Hematological oncology, 2016-03, Vol.34 (1), p.9-16
Ort / Verlag
England: Blackwell Publishing Ltd
Erscheinungsjahr
2016
Quelle
MEDLINE
Beschreibungen/Notizen
Advanced‐stage mycosis fungoides and Sezary syndrome (MF/SS) have a poor prognosis. Allogeneic hematopoietic stem cell transplantation (HSCT), particularly using a reduced‐intensity conditioning (RIC) regimen, is a promising treatment for advanced‐stage MF/SS. We performed RIC‐HSCT in nine patients with advanced MF/SS. With a median follow‐up period of 954 days after HSCT, the estimated 3‐year overall survival was 85.7% (95% confidence interval, 33.4–97.9%) with no non‐relapse mortality. Five patients relapsed after RIC‐HSCT; however, in four patients whose relapse was detected only from the skin, persistent complete response was achieved in one patient, and the disease was manageable in other three patients by the tapering of immunosuppressants and donor lymphocyte infusion, suggesting that graft‐versus‐lymphoma effect and ‘down‐staging’ effect from advanced stage to early stage by HSCT improve the prognosis of advanced‐stage MF/SS. These results suggest that RIC‐HSCT is an effective treatment for advanced MF/SS. Copyright © 2014 John Wiley & Sons, Ltd.
Sprache
Englisch
Identifikatoren
ISSN: 0278-0232
eISSN: 1099-1069
DOI: 10.1002/hon.2162
Titel-ID: cdi_proquest_miscellaneous_1776672406
Format
–
Schlagworte
Adult
,
allogeneic hematopoietic stem cell transplantation
,
Disease-Free Survival
,
Female
,
Follow-Up Studies
,
Graft vs Host Disease
,
Graft vs Tumor Effect
,
graft-versus-lymphoma effect
,
Humans
,
Immunosuppressive Agents - therapeutic use
,
Lymphocyte Transfusion
,
Male
,
Middle Aged
,
mycosis fungoides
,
Mycosis Fungoides - therapy
,
Neoplasm Recurrence, Local
,
Neoplasm Staging
,
Prognosis
,
reduced-intensity conditioning
,
Retrospective Studies
,
Sezary syndrome
,
Sezary Syndrome - therapy
,
Skin Neoplasms - therapy
,
Survival Rate
,
Transplantation Conditioning - methods
,
Transplantation, Homologous
,
Treatment Outcome
,
Young Adult
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX