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Exposure to synthetic oxytocin during delivery and its effect on psychomotor development
Developmental psychobiology, 2015-12, Vol.57 (8), p.908-920
González-Valenzuela, María-José
López-Montiel, Dolores
González-Mesa, Ernesto Santiago
2015
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
González-Valenzuela, María-José
López-Montiel, Dolores
González-Mesa, Ernesto Santiago
Titel
Exposure to synthetic oxytocin during delivery and its effect on psychomotor development
Ist Teil von
Developmental psychobiology, 2015-12, Vol.57 (8), p.908-920
Ort / Verlag
United States: Blackwell Publishing Ltd
Erscheinungsjahr
2015
Quelle
Wiley-Blackwell Journals
Beschreibungen/Notizen
ABSTRACT The main objective is to examine the influence of oxytocin administration during delivery on psychomotor development at age five years. This was a retrospective cohort study involving two groups: children of mothers exposed vs. not exposed to oxytocin during labor. Of the 7,465 newborns registered in our maternity service during 2006 we randomly selected an initial sample of 400 children. Of these, 146 children were assessed using the motor scale of the Battelle Developmental Inventory. Other predictor variables that could potentially act as confounders and/or interact with the main relationship were also examined. The data were subjected to bivariate analysis, estimates of measures of strength of association, stratified analysis and multivariate binary logistic regression. The results indicate that exposure to synthetic oxytocin during delivery is an independent risk factor for a delay in gross and fine motor development. This was the case after controlling for the variables duration of labor and sex of the newborn, none of which modified the effect of oxytocin on gross and fine motor development. However, sex of the newborn were shown to be confounding gross motor development. In light of these results, and with the aim of preventing possible psychomotor alterations, further studies are now needed to analyze the effect that the oxytocin dose and the duration of perfusion may have on children's subsequent development. © 2015 Wiley Periodicals, Inc. Dev Psychobiol 57: 908–920, 2015.
Sprache
Englisch
Identifikatoren
ISSN: 0012-1630
eISSN: 1098-2302
DOI: 10.1002/dev.21321
Titel-ID: cdi_proquest_miscellaneous_1776644229
Format
–
Schlagworte
Adult
,
Child Development - drug effects
,
Child, Preschool
,
Delivery, Obstetric - methods
,
Female
,
Humans
,
Infant, Newborn
,
Male
,
multivariate logistic regression
,
Oxytocics - administration & dosage
,
Oxytocics - therapeutic use
,
Oxytocin - administration & dosage
,
Oxytocin - therapeutic use
,
psychomotor development
,
Psychomotor Performance - drug effects
,
retrospective cohort study
,
Retrospective Studies
,
stratified analysis
,
synthetic oxytocin
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