Pediatric blood & cancer, 2016-05, Vol.63 (5), p.925-927
2016
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Details
- Autor(en) / Beteiligte
- Titel
- Central Diabetes Insipidus and Cisplatin-Induced Renal Salt Wasting Syndrome: A Challenging Combination
- Ist Teil von
- Pediatric blood & cancer, 2016-05, Vol.63 (5), p.925-927
- Ort / Verlag
- United States: Blackwell Publishing Ltd
- Erscheinungsjahr
- 2016
- Quelle
- Wiley Online Library Journals Frontfile Complete
- Beschreibungen/Notizen
- We describe a 2‐year‐old female with a suprasellar primitive neuroectodermal tumor and central diabetes insipidus (DI) who developed polyuria with natriuresis and subsequent hyponatremia 36 hr after cisplatin administration. The marked urinary losses of sodium in combination with a negative sodium balance led to the diagnosis of cisplatin‐induced renal salt wasting syndrome (RSWS). The subsequent clinical management is very challenging. Four weeks later she was discharged from ICU without neurological sequela. The combination of cisplatin‐induced RSWS with DI can be confusing and needs careful clinical assessment as inaccurate diagnosis and management can result in increased neurological injury.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1545-5009eISSN: 1545-5017DOI: 10.1002/pbc.25910Titel-ID: cdi_proquest_miscellaneous_1775381789
- Format
- –
- Schlagworte
- cerebral salt-wasting syndrome, Child, Preschool, Cisplatin - administration & dosage, Cisplatin - adverse effects, Diabetes, diabetes insipidus, Diabetes Insipidus, Neurogenic - chemically induced, Diabetes Insipidus, Neurogenic - diagnosis, Diabetes Insipidus, Neurogenic - urine, Female, Hematology, Humans, hyponatremia, Hyponatremia - chemically induced, Hyponatremia - diagnosis, Hyponatremia - urine, Neuroectodermal Tumors, Primitive - drug therapy, Oncology, Pediatrics, renal salt-wasting syndrome, syndrome of inappropriate antidiuretic hormone secretion, Wasting Syndrome - chemically induced, Wasting Syndrome - diagnosis, Wasting Syndrome - urine