Details

Autor(en) / Beteiligte

• Zhang, Xiao-Yan
• Yang, Zhi-Wei
• Chen, Zhongzhu
• Wang, Jun
• Yang, Dong-Lin
• Shen, Ze
• Hu, Li-Li
• Xie, Jian-Wu
• Zhang, Jin
• Cui, Hai-Lei

Titel

Tandem Copper-Catalyzed Propargylation/Alkyne Azacyclization/Isomerization Reaction under Microwave Irradiation: Synthesis of Fully Substituted Pyrroles

Ist Teil von

• Journal of organic chemistry, 2016-03, Vol.81 (5), p.1778-1785

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2016

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A copper-catalyzed and microwave-assisted synthesis of fully substituted pyrroles has been developed. A series of pentasubstituted pyrroles, especially α-arylpyrroles, could be obtained in moderate to good yields (up to 93%) through a tandem propargylation/​alkyne azacyclization/​isomerization sequence from readily available β-enamino compounds and propargyl acetates.