Lung cancer (Amsterdam, Netherlands), 2016-03, Vol.93, p.77-81
2016
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Details
- Autor(en) / Beteiligte
- Titel
- Medical treatment involving investigational drugs and genetic profile of thymic carcinoma
- Ist Teil von
- Lung cancer (Amsterdam, Netherlands), 2016-03, Vol.93, p.77-81
- Ort / Verlag
- Ireland: Elsevier B.V
- Erscheinungsjahr
- 2016
- Quelle
- Access via ScienceDirect (Elsevier)
- Beschreibungen/Notizen
- Highlights • Medical treatment and genetic profile of 64 thymic carcinoma were analyzed. • Investigational drugs involving multi-targeted TKIs exhibited potential efficacy. • Genetic alterations of TP53 , KRAS , FBXW7 , and NRAS were detected in 7 patients. • No apparent relationship between genetic alteration and the efficacy of chemotherapy.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0169-5002eISSN: 1872-8332DOI: 10.1016/j.lungcan.2016.01.004Titel-ID: cdi_proquest_miscellaneous_1767622755
- Format
- –
- Schlagworte
- Adult, Aged, Antineoplastic Agents - administration & dosage, Antineoplastic Agents - adverse effects, Antineoplastic Agents - therapeutic use, Biomarkers, Chemotherapy, Combined Modality Therapy, DNA Mutational Analysis, Drugs, Investigational - administration & dosage, Drugs, Investigational - adverse effects, Drugs, Investigational - therapeutic use, Female, Genetic profile, Hematology, Oncology and Palliative Medicine, Humans, Investigational drugs, Kaplan-Meier Estimate, Male, Middle Aged, Mutation, Neoplasm Staging, Next-generation sequencing, Pulmonary/Respiratory, Retrospective Studies, Thymic carcinoma, Thymus Neoplasms - diagnosis, Thymus Neoplasms - drug therapy, Thymus Neoplasms - genetics, Thymus Neoplasms - mortality, Treatment Outcome, Young Adult