Details

Autor(en) / Beteiligte

• Arcilla, Maris S
• van Hattem, Jarne M
• Matamoros, Sebastien
• Melles, Damian C
• Penders, John
• de Jong, Menno D
• Schultsz, Constance

Titel

Dissemination of the mcr-1 colistin resistance gene

Ist Teil von

• The Lancet infectious diseases, 2016-02, Vol.16 (2), p.147-149

Ort / Verlag

United States: Elsevier Ltd

Erscheinungsjahr

2016

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Supplementary Material   Traveller with isolate 1 Traveller with isolate 2 Traveller with isolate 3 Traveller with isolate 4 Traveller with isolate 5 Traveller with isolate 6 Travel destination Thailand, Vietnam, Cambodia, Laos Tunisia Peru, Bolivia, Colombia China China Peru, Bolivia Travel duration (days) 21 8 40 14 23 22 Age (years) 56 55 25 54 62 26 Sex Female Female Female Male Female Male ESBL gene (ESBL group) CTX-M-14 (CTX-M group 9) CTX-M-1 (CTX-M group 1) CTX-M-15 (CTX-M group 1) CTX-M-65 (CTX-M group 9) CTX-M-55 (CTX-M group 1) CTX-M-55 (CTX-M group 1) Minimum inhibitory concentration of antimicrobial drug (mg/L)*  Amoxicillin-clavulanic acid 16 8 >16 16 8 4  Piperacillin-tazobactam 8 <=4 8 <=4 <=4 <=4  Cefotaxime 16 8 32 16 >32 >32  Cefoxitin 16 <=4 8 <=4 <=4 <=4  Ceftazidime <=1 <=1 16 <=1 4 4  Cefepime 2 2 2 <=1 2 2  Imipenem <=0·25 <=0·25 <=0·25 <=0·25 <=0·25 <=0·25  Meropenem <=0·25 <=0·25 <=0·25 <=0·25 <=0·25 <=0·25  Gentamicin >8 <=1 >8 <=1 >8 <=1  Tobramycin 8 <=1 >8 8 8 <=1  Nitrofurantoin 256 <=16 128 32 64 <=16  Co-trimoxazole >8 >8 >8 <=1 >8 >8  Norfloxacin >8 8 >8 2 >8 >8  Ciprofloxacin >2 >2 >2 1 >2 >2  Colistin 4 4 4 4 4 8 Table Characteristics of travellers and acquired fecal Escherichia coli isolates carrying the mcr-1 gene ESBL=extended-spectrum β-lactamase.