Details

Autor(en) / Beteiligte

• Ureyen, I.
• Karalok, A.
• Tasci, T.
• Turkmen, O.
• Koc, S.
• Ozgul, A.
• Tulunay, G.
• Turan, T.

Titel

The importance of age and menopausal status in endometrial complex hyperplasia with atypia

Ist Teil von

• Journal of obstetrics and gynaecology, 2016-01, Vol.36 (1), p.102-105

Ort / Verlag

England: Taylor & Francis

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• The effects of menopausal status and age on the intra-operative and post-operative pathology results of patients operated on with a pre-operative diagnosis of complex hyperplasia with atypia (CHA) were assessed. A hundred and eleven patients diagnosed in our centre between January 1993 and March 2013 were included. Cancer was detected in the paraffin blocks (PBs) of 52 (46.8%) patients. Among these, 50 patients had stage-IA disease. In 31.1% of the pre-menopausal patients and 66% of the post-menopausal patients, PB revealed cancer (p < 0.0001). The results of frozen section (FS) and PB were concordant in 51% and 70% in the pre-menopausal and post-menopausal patients, respectively (p = 0.041). In the patients operated on with a pre-operative diagnosis of CHA, the probability of detecting cancer in PB increases with increasing age and menopause. The reliability of FS is limited in younger and pre-menopausal patients.