Brain research bulletin, 2016-01, Vol.120, p.83-89
2016
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Details
- Autor(en) / Beteiligte
- Titel
- Stress activates the nucleus incertus and modulates plasticity in the hippocampo-medial prefrontal cortical pathway
- Ist Teil von
- Brain research bulletin, 2016-01, Vol.120, p.83-89
- Ort / Verlag
- United States: Elsevier Inc
- Erscheinungsjahr
- 2016
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • Cold swim, swim or elevation stress induced c-Fos in the rat nucleus incertus (NI). • These stressors also impaired hippocampo-medial prefrontal cortical (HP-mPFC) LTP. • Intra-NI infusion of antalarmin (specific CRF1 antagonist) prevented elevation stress-induced suppression of HP-mPFC LTP. • NI-HP-mPFC is a stress responsive circuit in rodents.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0361-9230eISSN: 1873-2747DOI: 10.1016/j.brainresbull.2015.10.010Titel-ID: cdi_proquest_miscellaneous_1758240561
- Format
- –
- Schlagworte
- Animals, Brain Stem - drug effects, Brain Stem - pathology, Brain Stem - physiopathology, c-Fos, Catheters, Indwelling, Cold Temperature, Disease Models, Animal, Electrodes, Implanted, Fluorescent Antibody Technique, Hippocampus, Hippocampus - drug effects, Hippocampus - pathology, Hippocampus - physiopathology, Long-Term Potentiation - drug effects, Long-Term Potentiation - physiology, Male, Medial prefrontal cortex, Neural Pathways - drug effects, Neural Pathways - pathology, Neural Pathways - physiopathology, Neurology, Neurons - drug effects, Neurons - pathology, Neurons - physiology, Neurotransmitter Agents - pharmacology, Nucleus incertus, Plasticity, Prefrontal Cortex - drug effects, Prefrontal Cortex - pathology, Prefrontal Cortex - physiopathology, Proto-Oncogene Proteins c-fos - metabolism, Pyrimidines - pharmacology, Pyrroles - pharmacology, Rats, Sprague-Dawley, Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors, Receptors, Corticotropin-Releasing Hormone - metabolism, Stress, Stress, Psychological - drug therapy, Stress, Psychological - physiopathology, Swimming