Cancer research (Chicago, Ill.), 2005-04, Vol.65 (8), p.3049-3052
2005
Details
- Autor(en) / Beteiligte
- Titel
- Sv40 enhances the risk of malignant mesothelioma among people exposed to asbestos : A molecular epidemiologic case-control study
- Ist Teil von
- Cancer research (Chicago, Ill.), 2005-04, Vol.65 (8), p.3049-3052
- Ort / Verlag
- Philadelphia, PA: American Association for Cancer Research
- Erscheinungsjahr
- 2005
- Link zum Volltext
- Quelle
- Free E-Journal (出版社公開部分のみ）
- Beschreibungen/Notizen
- We conducted a case-control study on asbestos exposure and presence of SV40 in tumor samples of malignant mesotheliomas (MMs) and bladder urotheliomas (BUs). PCR analysis revealed the presence of SV40 DNA (SV40+) in eight (42.1%) MMs and 6 (33.3%) BUs. The odds ratio for MM Asb- and SV40+ was 0.4 [95% confidence interval (95% CI), 0.03-4.0], for Asb+ and SV40- was 3.6 (95% CI, 0.6-21.0), and for Asb+ and SV40+ was 12.6 (95% CI, 1.2-133.9). Our results suggest that SV40 increases the risk of MM among individuals exposed to asbestos.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0008-5472eISSN: 1538-7445DOI: 10.1158/0008-5472.can-04-2219Titel-ID: cdi_proquest_miscellaneous_17558125
- Format
- –
- Schlagworte
- Aged, Antineoplastic agents, Asbestos - poisoning, Biological and medical sciences, Case-Control Studies, Cocarcinogenesis, DNA, Neoplasm - genetics, Female, Humans, Male, Medical sciences, Mesothelioma - epidemiology, Mesothelioma - etiology, Mesothelioma - genetics, Mesothelioma - virology, Molecular Epidemiology, Pharmacology. Drug treatments, Polymerase Chain Reaction, Polyomavirus Infections - complications, Polyomavirus Infections - virology, Simian virus 40, Simian virus 40 - genetics, Simian virus 40 - physiology, Tumor Virus Infections - complications, Tumor Virus Infections - virology, Urinary Bladder Neoplasms - epidemiology, Urinary Bladder Neoplasms - etiology, Urinary Bladder Neoplasms - genetics, Urinary Bladder Neoplasms - virology