Details

Autor(en) / Beteiligte

• Due-Hansen, Maria E
• Pandey, Sunil K
• Christiansen, Elisabeth
• Andersen, Rikke
• Hansen, Steffen V F
• Ulven, Trond

Titel

A protocol for amide bond formation with electron deficient amines and sterically hindered substrates

Ist Teil von

• Organic & biomolecular chemistry, 2016-01, Vol.14 (2), p.430-433

Ort / Verlag

England

Erscheinungsjahr

2016

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A protocol for amide coupling by in situ formation of acyl fluorides and reaction with amines at elevated temperature has been developed and found to be efficient for coupling of sterically hindered substrates and electron deficient amines where standard methods failed.