Details

Autor(en) / Beteiligte

• Konkala, Karnakar
• Sabbavarapu, Narayana Murthy
• Katla, Ramesh
• Durga, Nageswar Yadavalli Venkata
• Kumar Reddy T, Vijai
• Bethala L.A., Prabhavathi Devi
• Rachapudi B.N., Prasad

Titel

Revisit to the Biginelli reaction: a novel and recyclable bioglycerol-based sulfonic acid functionalized carbon catalyst for one-pot synthesis of substituted 3,4-dihydropyrimidin-2-(1H)-ones

Ist Teil von

• Tetrahedron letters, 2012-04, Vol.53 (15), p.1968-1973

Ort / Verlag

Elsevier Ltd

Erscheinungsjahr

2012

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• A simple and efficient synthetic protocol has been developed for the synthesis of 3,4-dihydropyrimidin-2-(1H)-ones by using a novel bioglycerol-based sulfonic acid functionalized carbon catalyst, devoid of moisture sensitive metal catalysts and corrosive acidic reagents. The developed method has the advantages of good to excellent yields, short reaction times, operational simplicity, and a recyclable catalyst. The catalyst can be prepared by a simple procedure from inexpensive and readily available glycerol and has been shown to be recoverable and reusable up to four cycles without any loss of activity.