Details

Autor(en) / Beteiligte

• Chua, Sin-Siu
• Alni, Anita
• Jocelyn Chan, Li-Ting
• Yamane, Motoki
• Loh, Teck-Peng

Titel

Indium(III) chloride-catalyzed Mukaiyama–Michael addition: synthesis of 2,6- anti-tetrahydropyrans

Ist Teil von

• Tetrahedron, 2011-07, Vol.67 (27), p.5079-5082

Ort / Verlag

Elsevier Ltd

Erscheinungsjahr

2011

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• In the presence of a catalytic amount of indium(III) chloride (InCl 3), silyl enol ethers react with dihydropyranones at ambient temperature via Mukaiyama–Michael addition to afford the corresponding 2,6-anti-tetrahydropyran adducts in moderate to good yields. This simple and mild method proceeds under neat conditions and involves simple aqueous work-up. Indium(III) chloride can be recovered and reused without significant decrease in reactivity. [Display omitted]