Details

Autor(en) / Beteiligte

• Marin, Samantha E., MD
• Saneto, Russell P., DO, PhD

Titel

Neuropsychiatric Features in Primary Mitochondrial Disease

Ist Teil von

• Neurologic clinics, 2016-02, Vol.34 (1), p.247-294

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Mitochondrial diseases are a clinically heterogeneous group of disorders that ultimately result from dysfunction of the mitochondrial respiratory chain. There is some evidence to suggest that mitochondrial dysfunction plays a role in neuropsychiatric illness; however, the data are inconclusive. This article summarizes the available literature published in the area of neuropsychiatric manifestations in both children and adults with primary mitochondrial disease, with a focus on autism spectrum disorder in children and mood disorders and schizophrenia in adults.