Details

Autor(en) / Beteiligte

• Wright, Elizabeth
• Fischbach, Michel
• Zaloszyc, Ariane
• Paglialonga, Fabio
• Aufricht, Christoph
• Dufek, Stephanie
• Bakkaloğlu, Sevcan
• Klaus, Günter
• Zurowska, Aleksandra
• Ekim, Mesiha
• Ariceta, Gema
• Holtta, Tuula
• Jankauskiene, Augustina
• Schmitt, Claus Peter
• Stefanidis, Constantinos J.
• Walle, Johan Vande
• Vondrak, Karel
• Edefonti, Alberto
• Shroff, Rukshana

Titel

Hemodialysis in children with ventriculoperitoneal shunts: prevalence, management and outcomes

Ist Teil von

• Pediatric nephrology (Berlin, West), 2016-01, Vol.31 (1), p.137-143

Ort / Verlag

Berlin/Heidelberg: Springer Berlin Heidelberg

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Background Hemodialysis (HD) in children with a concomitant ventriculoperitoneal shunt (VPS) is rare. Registry data suggest that peritoneal dialysis with a VPS is safe, but little is known about HD in the presence of a VPS. Methods We performed a 10-year survey to determine the prevalence of a VPS, complications and outcome in children with a VPS on HD in 15 dialysis units from the 13 countries participating in the European Pediatric Dialysis Working Group. Results Eleven cases of HD with a VPS were reported (prevalence 1.33 %; 328 patient-months) and compared with prospective Registry data. The median age at start of dialysis was 9.6 [inter-quartile range (IQR) 1.0–15.0] years and median HD vintage was 2.4 (IQR 1.7–3.0) years. Dialysis was performed through a central venous line (CVL) and through an arteriovenous fistula in six and five children, respectively. Three CVL infections occurred in two children, but these children did not develop VPS infections or meningitis. Symptoms of hemodynamic instability were reported in six (55 %) children at least once per week, with hypotension or hypertension occurring in four of these children and nausea, vomiting and headaches occurring in two; four other children reported less frequent symptoms. Seizures on dialysis occurred in two children, at a frequency of less than once per month, with one child also experiencing visual disturbances. During follow-up (median 4.0; IQR 0.38–7.63 years), three children remained on HD and eight had a functioning transplant. No patients were switched to PD. Conclusions Hemodialysis in children with a VPS is safe, but associated with frequent symptoms of hemodynamic instability. No episodes of VPS infection or meningitis were seen among the children in the survey, not even in those with CVL sepsis.