Dalton transactions : an international journal of inorganic chemistry, 2013-10, Vol.42 (37), p.13343-13348
2013
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Details
- Autor(en) / Beteiligte
- Titel
- Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand
- Ist Teil von
- Dalton transactions : an international journal of inorganic chemistry, 2013-10, Vol.42 (37), p.13343-13348
- Ort / Verlag
- England
- Erscheinungsjahr
- 2013
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- In this communication, we present the synthesis of new platinum complexes based on hydroxyquinoline ligands. We demonstrate the importance and the role of the halogen substitution as well as the chelation, which are essential structural characteristics for finding good cytotoxicities.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1477-9226eISSN: 1477-9234DOI: 10.1039/c3dt51720aTitel-ID: cdi_proquest_miscellaneous_1730079409
- Format
- –
- Schlagworte
- Antineoplastic Agents - chemical synthesis, Antineoplastic Agents - chemistry, Antineoplastic Agents - pharmacology, Cell Line, Tumor, Cell Proliferation - drug effects, Chelation, Clioquinol - chemistry, Crystallography, X-Ray, Dose-Response Relationship, Drug, Drug Screening Assays, Antitumor, Halogens, Halogens - chemistry, HeLa Cells, Humans, Hydroxyl groups, Hydroxyquinoline, Hydroxyquinolines - chemistry, Ligands, Models, Molecular, Molecular Structure, Organoplatinum Compounds - chemical synthesis, Organoplatinum Compounds - chemistry, Organoplatinum Compounds - pharmacology, Platinum, Structure-Activity Relationship, Synthesis