Details

Autor(en) / Beteiligte

• Bakkal, Faruk Kadri, MD
• Başman, Adil, DMD
• Kızıl, Yusuf, MD
• Ekinci, Özgür, MD
• Gümüşok, Mustafa, DMD
• Ekrem Zorlu, Mehmet, MD
• Aydil, Utku, MD

Titel

Mucosal melanoma of the head and neck: recurrence characteristics and survival outcomes

Ist Teil von

• Oral surgery, oral medicine, oral pathology and oral radiology, 2015-11, Vol.120 (5), p.575-580

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2015

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Objective The aim of this study was to review oncologic outcomes and recurrence characteristics of head and neck mucosal melanomas (HNMMs) managed at a tertiary referral center. Study Design Clinical records of 10 patients who were managed for HNMMs between 2001 and 2013 were retrospectively analyzed. Results The median age was 66 years (range 28-76 years) and male/female (M/F) ratio was 1:5. The 3-year disease-free survival (DFS) rates and overall survival (OS) rates were 11.7% and 35%, respectively; and the 5-year DFS rates and OS rates 11.7% and 23.3%, respectively. The median DFS and OS periods were 12 months (range 2-36 months) and 17 months (range 7-96 months), respectively. The rates of development of local, regional, and systemic recurrences were 20%, 50%, and 80%, respectively. Lungs were involved in all patients who had distant metastasis. Conclusions This study shows that HNMMs has a very aggressive course and that distant metastases are common. For this reason, systemic control of the disease is an important aim of treatment.