Details

Autor(en) / Beteiligte

• Loos, Bruno G., DDS, MSc, PhD
• Papantonopoulos, Georgios, DDS, MSc
• Jepsen, Søren, DDS, MSc, PhD
• Laine, Marja L., DDS, PhD

Titel

What is the Contribution of Genetics to Periodontal Risk?

Ist Teil von

• The Dental clinics of North America, 2015-10, Vol.59 (4), p.761-780

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• This review addresses the multicausal etiology of periodontitis, in which genetic factors play a role. The various proposed causes for periodontitis always work simultaneously, but the relative contribution of each of these varies from case to case. We are still at an early stage to identify the genes involved, in comparison with other chronic diseases. To date, the genetic variations firmly and repeatedly associated with periodontitis in some populations are found within the following genes: ANRIL, COX2, IL1, IL10, DEFB1, whereas many other proposed periodontitis candidate genes have not been firmly proven or replicated.