Clinical lymphoma, myeloma and leukemia, 2015-10, Vol.15 (10), p.606-611
2015
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Central Nervous System Complications and Outcomes After Allogeneic Hematopoietic Stem Cell Transplantation
- Ist Teil von
- Clinical lymphoma, myeloma and leukemia, 2015-10, Vol.15 (10), p.606-611
- Ort / Verlag
- United States: Elsevier Inc
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Micro-Abstract This retrospective study of 351 patients who underwent allogeneic hematopoietic stem cell transplantation between 2002 and 2011 at the University of Nebraska Medical Center demonstrated 12% incidence of central nervous system complications (CNSC). The most common complications included posterior reversible encephalopathy syndrome (40%), stroke or transient ischemic attack (24%), seizures (20%), and infection (9%). The 5-year overall survival was significantly lower among patients with versus without CNSC (14% vs. 44%, P = .0004).
- Sprache
- Englisch
- Identifikatoren
- ISSN: 2152-2650eISSN: 2152-2669DOI: 10.1016/j.clml.2015.06.004Titel-ID: cdi_proquest_miscellaneous_1718904080
- Format
- –
- Schlagworte
- Adolescent, Adult, Aged, Allogeneic hematopoietic stem cell transplantation, Central nervous system complications, Child, Child, Preschool, Female, Hematology, Oncology and Palliative Medicine, Hematopoietic Stem Cell Transplantation - adverse effects, Humans, Infant, Leukemia, Myeloid, Acute - mortality, Leukemia, Myeloid, Acute - therapy, Male, Middle Aged, Multivariate Analysis, Posterior Leukoencephalopathy Syndrome - etiology, Posterior Leukoencephalopathy Syndrome - mortality, Posterior reversible encephalopathy syndrome, Proportional Hazards Models, Retrospective Studies, Risk Factors, Seizure, Seizures - etiology, Seizures - mortality, Stroke, Stroke - etiology, Stroke - mortality, Survival, Transplantation, Homologous, Treatment Outcome, Young Adult