Details

Autor(en) / Beteiligte

• Cunha, Burke A., MD
• Lortholary, Olivier, MD, PhD
• Cunha, Cheston B., MD

Titel

Fever of Unknown Origin: A Clinical Approach

Ist Teil von

• The American journal of medicine, 2015-10, Vol.128 (10), p.1138.e1-1138.e15

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2015

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Abstract Fevers of unknown origin remain one of the most difficult diagnostic challenges in medicine. Because fever of unknown origin may be caused by over 200 malignant/neoplastic, infectious, rheumatic/inflammatory, and miscellaneous disorders, clinicians often order non-clue-based imaging and specific testing early in the fever of unknown origin work-up, which may be inefficient/misleading. Unlike most other fever-of-unknown-origin reviews, this article presents a clinical approach. Characteristic history and physical examination findings together with key nonspecific test abnormalities are the basis for a focused clue-directed fever of unknown origin work-up.