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Complete response of huge buccal malignant melanoma in an octogenarian patient to arterial chemotherapy
Head & neck, 2015-10, Vol.37 (10), p.E134-E138
Wu, Chih‐Feng
Wu, Chieh‐Shan
Yu, Wei‐Wen
Huang, Ming‐Yii
Andersen, Peter
2015
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Wu, Chih‐Feng
Wu, Chieh‐Shan
Yu, Wei‐Wen
Huang, Ming‐Yii
Andersen, Peter
Titel
Complete response of huge buccal malignant melanoma in an octogenarian patient to arterial chemotherapy
Ist Teil von
Head & neck, 2015-10, Vol.37 (10), p.E134-E138
Ort / Verlag
United States: Wiley Subscription Services, Inc
Erscheinungsjahr
2015
Quelle
Wiley Online Library All Journals
Beschreibungen/Notizen
Background Primary oral mucosal melanoma is uncommon. However, it is an aggressive entity, and the absence of a standardized treatment protocol makes for an extremely poor prognosis. Methods We described the clinical course and treatment by arterial chemotherapy of an 87‐year‐old patient with nonresectable huge buccal malignant melanoma. Continuous intra‐arterial infusion of fluorouracil (50 mg/24 hours) and 1 intermittent weekly 10‐mg shot of cisplatin were given. Results The patient with oral melanoma presented with a roughly 6‐ × 4‐cm exophytic mass that was noticed on the right buccal mucosa. The buccal tumor regressed dramatically until complete disappearance of the tumor mass was achieved at 2.5 months after intra‐arterial chemotherapy was initiated. In total, 2880 mg of fluorouracil and 80 mg of cisplatin were administrated. The side effects of intra‐arterial chemotherapy were mild and tolerable. Conclusion Our data demonstrate that intra‐arterial chemotherapy could be an alternative treatment for nonresectable buccal malignant melanoma. © 2015 Wiley Periodicals, Inc. Head Neck 37: E134–E138, 2015
Sprache
Englisch
Identifikatoren
ISSN: 1043-3074
eISSN: 1097-0347
DOI: 10.1002/hed.23941
Titel-ID: cdi_proquest_miscellaneous_1713529130
Format
–
Schlagworte
Aged, 80 and over
,
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
,
buccal mucosa
,
Cisplatin - administration & dosage
,
complete response
,
Fluorouracil - administration & dosage
,
Humans
,
Infusions, Intra-Arterial
,
intra‐arterial infusion chemotherapy
,
Male
,
malignant melanoma
,
Melanoma - drug therapy
,
Mouth Mucosa - pathology
,
Mouth Neoplasms - drug therapy
,
Mouth Neoplasms - pathology
,
oral cavity
,
Remission Induction
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