Journal of agricultural and food chemistry, 2015-09, Vol.63 (35), p.7707-7713
2015
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Bactericidal Activity and Mechanism of Photoirradiated Polyphenols against Gram-Positive and -Negative Bacteria
- Ist Teil von
- Journal of agricultural and food chemistry, 2015-09, Vol.63 (35), p.7707-7713
- Ort / Verlag
- United States: American Chemical Society
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The bactericidal effect of various types of photoirradiated polyphenols against Gram-positive and -negative bacteria was evaluated in relation to the mode of action. Gram-positive bacteria (Enterococcus faecalis, Staphylococcus aureus, and Streptococcus mutans) and Gram-negative bacteria (Aggregatibacter actinomycetemcomitans, Escherichia coli, and Pseudomonas aeruginosa) suspended in a 1 mg/mL polyphenol aqueous solution (caffeic acid, gallic acid, chlorogenic acid, epigallocatechin, epigallocatechin gallate, and proanthocyanidin) were exposed to LED light (wavelength, 400 nm; irradiance, 260 mW/cm2) for 5 or 10 min. Caffeic acid and chlorogenic acid exerted the highest bactericidal activity followed by gallic acid and proanthocyanidin against both Gram-positive and -negative bacteria. It was also demonstrated that the disinfection treatment induced oxidative damage of bacterial DNA, which suggests that polyphenols are incorporated into bacterial cells. The present study suggests that blue light irradiation of polyphenols could be a novel disinfection treatment.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0021-8561eISSN: 1520-5118DOI: 10.1021/jf5058588Titel-ID: cdi_proquest_miscellaneous_1710983267
- Format
- –
- Schlagworte
- Anti-Bacterial Agents - chemistry, Anti-Bacterial Agents - pharmacology, DNA Damage - drug effects, DNA Damage - radiation effects, Gram-Negative Bacteria - drug effects, Gram-Negative Bacteria - genetics, Gram-Negative Bacteria - metabolism, Gram-Negative Bacteria - radiation effects, Gram-Positive Bacteria - drug effects, Gram-Positive Bacteria - genetics, Gram-Positive Bacteria - metabolism, Gram-Positive Bacteria - radiation effects, Light, Microbial Sensitivity Tests, Oxidative Stress - drug effects, Oxidative Stress - radiation effects, Plant Extracts - chemistry, Plant Extracts - pharmacology, Polyphenols - chemistry, Polyphenols - pharmacology