Details

Autor(en) / Beteiligte

• Schietroma, Mario, M.D
• Pessia, Beatrice, M.D
• Carlei, Francesco, M.D
• Cecilia, Emanuela Marina, M.D
• De Santis, Giuseppe, M.D
• Amicucci, Gianfranco, M.D

Titel

Laparoscopic versus open colorectal surgery for colon cancer: the effect of surgical trauma on the bacterial translocation. A prospective randomized study

Ist Teil von

• The American journal of surgery, 2015-08, Vol.210 (2), p.263-269

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract Background Several studies suggest that surgical manipulation of the intestine and increased intra-abdominal pressure promotes bacterial translocation (BT). This prospective randomized study has investigated the effect of surgery on BT in patients undergoing elective colectomy for colon cancer by comparing the laparoscopic with the open approach. Methods One hundred nineteen consecutive patients underwent colectomy for colon cancer: 59 cases underwent open resection and 60 cases underwent laparoscopic resection. For bacterial identification, tissue samples were taken from the liver, spleen, and mesenteric lymph nodes. Results The incidence of BT increased in laparoscopic and open group after bowel mobilization (prior to ligation of the vascular pedicle), compared with the before mobilization ( P < .05). There was not a statistically significant difference in BT value between the 2 groups. Conclusion BT increase was observed during the open and laparoscopic resection for colon cancer, without significant statistical difference between the 2 groups.