Trends in Biochemical Sciences, 1995-10, Vol.20 (10), p.391-397
1995
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Details
- Autor(en) / Beteiligte
- Titel
- The base excision repair pathway
- Ist Teil von
- Trends in Biochemical Sciences, 1995-10, Vol.20 (10), p.391-397
- Ort / Verlag
- England: Elsevier Ltd
- Erscheinungsjahr
- 1995
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The base excision repair pathway has evolved to protect cells from the deleterious effects of endogenous DNA damage induced by hydrolysis, reactive oxygen species and other intracellular metabolites that modify DNA base structure. However, base excision repair is also important to resist lesions produced by ionizing radiation and strong alkylating agents, which are similar to those induced by endogenous factors.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0968-0004eISSN: 1362-4326DOI: 10.1016/S0968-0004(00)89086-6Titel-ID: cdi_proquest_miscellaneous_17091489