Sleep medicine, 2015-09, Vol.16 (9), p.1102-1108
2015
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Effect of oral JZP-110 (ADX-N05) treatment on wakefulness and sleepiness in adults with narcolepsy
- Ist Teil von
- Sleep medicine, 2015-09, Vol.16 (9), p.1102-1108
- Ort / Verlag
- Netherlands: Elsevier B.V
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • JZP-110 is a wake-promoting agent with dopaminergic and noradrenergic activity. • JZP-110 resulted in greater changes in sleep latency on each Maintenance of Wakefulness Test (MWT) trial. • For Epworth Sleepiness Scale (ESS), JZP-110 was more efficacious relative to placebo after 1 and 2 weeks. • Efficacy of JZP-110 was observed as early as 1 week after treatment.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1389-9457eISSN: 1878-5506DOI: 10.1016/j.sleep.2015.05.013Titel-ID: cdi_proquest_miscellaneous_1706578268
- Format
- –
- Schlagworte
- Administration, Oral, Adult, Cross-Over Studies, Double-Blind Method, Epworth Sleepiness Scale, Excessive sleepiness, Female, Humans, JZP-110, Maintenance of Wakefulness Test, Male, Middle Aged, Narcolepsy, Narcolepsy - complications, Narcolepsy - drug therapy, Narcolepsy - physiopathology, Neurology, Phenylalanine - analogs & derivatives, Phenylalanine - therapeutic use, Sleep Medicine, Sleep-onset latency, Treatment Outcome, Wakefulness - drug effects