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Reliability of Small Biopsy Samples Compared With Resected Specimens for the Determination of Programmed Death-Ligand 1 Expression in Non–Small-Cell Lung Cancer
Micro-Abstract Expression of programmed death-ligand 1 (PD-L1) in non–small-cell lung cancer (NSCLC) has mainly been examined using surgically resected specimens. We retrospectively evaluated the expression of PD-L1 using immunohistochemistry in 79 paired small biopsy and resected specimens of NSCLC. The concordance between the samples was good, with a concordance rate of 92.4% and κ value of 0.8366.