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Potency of 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126), alone and in combination with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), to produce lake trout early life-stage mortality
Ist Teil von
Environmental toxicology and chemistry, 1995-12, Vol.14 (12), p.2175-2179
Ort / Verlag
Hoboken: Wiley Periodicals, Inc
Erscheinungsjahr
1995
Beschreibungen/Notizen
Newly fertilized lake trout (Salvelinus namaycush) eggs were exposed to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD), 3,3′,4,4′,5‐pentachlorobiphenyl (PCB 126), or their combination, and sac fry mortality was used to determine toxic potencies. The toxic equivalency factor (TEF) for PCB 126 was 0.0030. The dose‐response curve for the PCB 126/TCDD mixture based on TCDD toxic equivalents was not significantly different from that for TCDD alone, suggesting additivity between the two congeners in causing sac fry mortality.