Angewandte Chemie International Edition, 2013-11, Vol.52 (47), p.12359-12363
International ed. in English, 2013
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation
- Ist Teil von
- Angewandte Chemie International Edition, 2013-11, Vol.52 (47), p.12359-12363
- Auflage
- International ed. in English
- Ort / Verlag
- Weinheim: WILEY-VCH Verlag
- Erscheinungsjahr
- 2013
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- A series of tubes: The continuous manufacture of a finished drug product starting from chemical intermediates is reported. The continuous pilot‐scale plant used a novel route that incorporated many advantages of continuous‐flow processes to produce active pharmaceutical ingredients and the drug product in one integrated system.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1433-7851eISSN: 1521-3773DOI: 10.1002/anie.201305429Titel-ID: cdi_proquest_miscellaneous_1701115691
- Format
- –
- Schlagworte
- Acids - chemistry, Amides - chemical synthesis, Amides - chemistry, Amides - isolation & purification, Catalysis, continuous processing, Crystallization, Dosage, Drug Compounding, Drugs, flow chemistry, Formations, Fumarates - chemical synthesis, Fumarates - chemistry, Fumarates - isolation & purification, Ingredients, lactones, Pharmaceutical Preparations - chemical synthesis, Pharmaceutical Preparations - chemistry, Pharmaceutical Preparations - isolation & purification, Pharmaceuticals, protecting groups, Purification, Synthesis, synthetic methods, Technology, Pharmaceutical, Tubes