Details

Autor(en) / Beteiligte

• Fuchs, Sebastian W.
• Bozhüyük, Kenan A. J.
• Kresovic, Darko
• Grundmann, Florian
• Dill, Veronica
• Brachmann, Alexander O.
• Waterfield, Nicholas R.
• Bode, Helge B.

Titel

Formation of 1,3-Cyclohexanediones and Resorcinols Catalyzed by a Widely Occuring Ketosynthase

Ist Teil von

• Angewandte Chemie (International ed.), 2013-04, Vol.52 (15), p.4108-4112

Auflage

International ed. in English

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2013

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Overlooked, but widespread! A new class of ketosynthases (DarB) involved in the biosynthesis of 1,3‐cyclohexanediones and dialkylresorcinols has been identified and characterized in detail. The presence of homologues in 89 different bacteria, including several pathogens, reveals that DarB as well as the corresponding natural products might be widespread, thus presenting a new but so far overlooked pathway to natural products.