Brain, behavior, and immunity, 2015-08, Vol.48, p.165-173
2015
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Details
- Autor(en) / Beteiligte
- Titel
- Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour
- Ist Teil von
- Brain, behavior, and immunity, 2015-08, Vol.48, p.165-173
- Ort / Verlag
- Netherlands: Elsevier Inc
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • High doses of antibiotics from weaning depleted and restructured the gut microbiota. • Gut microbiota depletion was paralleled by impaired cognition and decreased anxiety. • Antibiotics altered levels of neuromodulators communicating along the microbiota–gut–brain axis. • Antibiotics provide a means of assessing the temporal importance of gut bacteria in brain development.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0889-1591eISSN: 1090-2139DOI: 10.1016/j.bbi.2015.04.004Titel-ID: cdi_proquest_miscellaneous_1697757184
- Format
- –
- Schlagworte
- Adolescence, Allergy and Immunology, Animals, Anti-Bacterial Agents - pharmacology, Antibiotics, Anxiety, BDNF, Behavior, Animal - drug effects, Behavior, Animal - physiology, Body Weight - drug effects, Body Weight - physiology, Brain - drug effects, Brain - metabolism, Brain - physiology, Brain-Derived Neurotrophic Factor - metabolism, Cognition, Gastrointestinal Microbiome - drug effects, Gastrointestinal Microbiome - physiology, Gastrointestinal Tract - microbiology, Gut microbiota, Mice, Psychiatry, Tryptophan - metabolism, Vasopressin