Details

Autor(en) / Beteiligte

• Nichol, Graham
• Guffey, Danielle
• Stiell, Ian G
• Leroux, Brian
• Cheskes, Sheldon
• Idris, Ahamed
• Kudenchuk, Peter J
• Macphee, Renee S
• Wittwer, Lynn
• Rittenberger, Jon C
• Rea, Thomas D
• Sheehan, Kellie
• Rac, Val E
• Raina, Keitki
• Gorman, Kyle
• Aufderheide, Tom

Titel

Post-discharge outcomes after resuscitation from out-of-hospital cardiac arrest: A ROC PRIMED substudy

Ist Teil von

• Resuscitation, 2015-08, Vol.93, p.74-81

Ort / Verlag

Ireland: Elsevier Ireland Ltd

Erscheinungsjahr

2015

Quelle

Elsevier ScienceDirect Journals

Beschreibungen/Notizen

• Abstract Importance Assessment of morbidity is an important component of evaluating interventions for patients with out-of-hospital cardiac arrest (OHCA). Objective We evaluated among survivors of OHCA cognition, functional status, health-related quality of life and depression as functions of patient and emergency medical services (EMS) factors. Design Prospective cohort sub-study of a randomized trial. Setting The parent trial studied two comparisons in persons with non-traumatic OHCA treated by EMS personnel participating in the Resuscitation Outcomes Consortium. Participants Consenting survivors to discharge. Main outcome measures Telephone assessments up to 6 months after discharge included neurologic function (modified Rankin score, MRS), cognitive impairment (Adult Lifestyle and Function Mini Mental Status Examination, ALFI-MMSE), health-related quality of life (Health Utilities Index Mark 3, HUI3) and depression (Telephone Geriatric Depression Scale, T-GDS). Results Of 15,794 patients enrolled in the parent trial, 729 (56% of survivors) consented. About 644 respondents (88% of consented) completed ≥ 1 assessment. Likelihood of assessment was associated with baseline characteristics and study site. Most respondents had MRS ≤ 3 (82.7%), no cognitive impairment (82.7% ALFI-MMSE ≥ 17), no severe impairment in health (71.6%, HUI3 ≥ 0.7) and no depression (90.1% T-GDS ≤ 10). Outcomes did not differ by trial intervention or time from hospital discharge. Conclusions and relevance The majority of patients in this large cohort who survived cardiac arrest and were interviewed had no, mild or moderate health impairment. Concern about poor quality of life is not a valid reason to abandon efforts to improve an EMS system's response to cardiac arrest.