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Role of serum antibodies in protection of vaccinated turbot ( Scophthalmus maximus) against vibriosis
Ist Teil von
Aquaculture, 1994-06, Vol.123 (3), p.197-204
Ort / Verlag
Amsterdam: Elsevier B.V
Erscheinungsjahr
1994
Quelle
Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)
Beschreibungen/Notizen
We evaluated serum antibody production, and mortality following severe intraperitoneal challenge with
Vibrio anguillarum, in turbot (
Scophthalmus maximus) which had been immersion-and/or injection-vaccinated with toxoid-enriched whole cells of the
V. anguillarum virulent wild strain R-82. Our results show: (a) that immersion vaccination does not provoke appreciable increases in serum antibody levels; (b) that enzyme-linked immunosorbent assay with a monoclonal antibody to turbot Ig is (unlike agglutination assay) sufficiently sensitive for quantitating post-vaccination serum antibody production in turbot; and (c) that immersion vaccination (unless followed by an intraperitoneal booster) does not protect turbot against severe challenge with a
V. anguillarum virulent strain. These results strongly suggest that the protection against challenge provided by injection is mediated by serum antibodies.