Details

Autor(en) / Beteiligte

• Oludina, Yu. N.
• Sazykina, M. A.
• Prazdnova, E. V.
• Sazykin, I. S.
• Khmelevtsova, L. E.
• Bukharov, S. V.
• Barsukova, T. A.
• Tagasheva, R. G.
• Nugumanova, G. N.

Titel

Synthesis of Modified Sterically Hindered Phenols and Investigation of Their Ability to Protect Bacterial DNA Against UVB Damage

Ist Teil von

• Pharmaceutical chemistry journal, 2015-03, Vol.48 (12), p.787-790

Ort / Verlag

New York: Springer US

Erscheinungsjahr

2015

Quelle

SpringerNature Journals

Beschreibungen/Notizen

• New derivatives of sterically hindered phenols were obtained. Their DNA-protective activity under UV irradiation was studied. The experimental results showed that the investigated compounds protected genetic material from both direct UVB radiation and reactive oxygen species generated in the cell by it. The new compounds were promising components for preparations that protect DNA from UV-radiation-induced damage.