Details

Autor(en) / Beteiligte

• Kukushkin, NI
• Obraztsov, V V
• Tarakhovskii, YuS
• Ponomarchuk, V V
• Sklifas, AN

Titel

On biophysics mechanisms of toxicity of fluorocarbon emulsions

Ist Teil von

• Artificial cells, blood substitutes, and immobilization biotechnology, 1994-11, Vol.22 (5), p.A120-A120

Erscheinungsjahr

1994

Quelle

Taylor & Francis Journals Auto-Holdings Collection

Beschreibungen/Notizen

• The simple working model for the pulmonary gas trapping (PGT) is presented. It is the contact between the air and hydrogen separated by porous partition that results in the appearance of the additional pressure in the compartment containing more heavy gas. Theoretical and experimental analysis show that an absence of emulsion particle aggregation in the blood stream, a low pressure of saturated vapors of the perfluorocarbon phase and a relatively low velocity of PFC expiration from the organism are essential conditions for the creation of a safe fluorocarbon blood substitute.