Details

Autor(en) / Beteiligte

• Ofran, Yishai
• Filanovsky, Kalman
• Gafter-Gvili, Anat
• Vidal, Liat
• Aviv, Ariel
• Gatt, Moshe E
• Silbershatz, Itay
• Herishanu, Yair
• Arad, Ariela
• Tadmor, Tamar
• Dally, Najib
• Nemets, Anatoly
• Rouvio, Ory
• Ronson, Aharon
• Herzog-Tzarfati, Katrin
• Akria, Luiza
• Braester, Andrei
• Hellmann, Ilana
• Yeganeh, Shay
• Nagler, Arnon
• Leiba, Ronit
• Mittelman, Moshe
• Merkel, Drorit

Titel

Higher Infection Rate After 7- Compared With 5-Day Cycle of Azacitidine in Patients With Higher-Risk Myelodysplastic Syndrome

Ist Teil von

• Clinical lymphoma, myeloma and leukemia, 2015-06, Vol.15 (6), p.e95-e99

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2015

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Micro-Abstract Azacitidine (AZA) dose reduction is a common practice in cytopenic patients. We herein report on a correlation between AZA dose and infection complications in high-risk myelodysplastic syndrome and leukemia patients. Infectious events were more frequent after doses of 75 mg/m2 for 7 days than 75 mg/m2 for 5 days, regardless of the patient's age. Reduction of AZA dose should therefore be considered in patients with high infection risk.