Details

Autor(en) / Beteiligte

• Kim, Yerim, MD, MSc
• Kang, Dong-Wan, MD
• Kim, Do Yeon, MD
• Pyun, Jung Min, MD
• Lee, Seung-Hoon, MD, PhD

Titel

Branch-Duct Intraductal Papillary Mucinous Neoplasm and Embolic Stroke of Unknown Cause

Ist Teil von

• Journal of stroke and cerebrovascular diseases, 2015-06, Vol.24 (6), p.e143-e145

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• Background In many embolic strokes, the specific embolic source might be uncertain. When we found asymptomatic branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) in patients with ischemic stroke of unknown cause, most of gastroenterologists might undervalue it as a potential thromboembolic sources. Methods We report 4 patients with embolic stroke of unknown cause and incidental BD-IPMNs. Results Magnetic resonance imaging revealed multiple embolic infarctions. Recommended cardiac examinations, such as 24-hour Holter monitoring and transthoracic and transesophageal echocardiography, were normal. Other cancer markers and molecular markers of hypercoagulopathy were normal. On abdominal computed tomography scan, performed to detect hidden malignancy, a low attenuated lesion with a diameter of less than 3 cm was observed in the pancreas. Conclusion Although BD-IPMNs are associated with a lower rate of malignancy than main-duct IPMNs, the BD-IPMNs had some malignant potential and frequently coexist with extrapancreatic or intrapancreatic cancers. Therefore, we suggest that, in some cases, the BD-IPMNs might be considered as a thromboembolic source.