Details

Autor(en) / Beteiligte

• Helma, Christoph
• Kronberg, Leif
• Ma, Te-Hsiu
• Knasmüller, Siegfried

Titel

Genotoxic effects of the chlorinated hydroxyfuranones 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5 H]-furanone and 3,4-dichloro-5-hydroxy-2[5 H]-furanone in Tradescantia micronucleus assays

Ist Teil von

• Mutation research, 1995-03, Vol.346 (3), p.181-186

Ort / Verlag

Amsterdam: Elsevier B.V

Erscheinungsjahr

1995

Quelle

Elsevier Journal Backfiles on ScienceDirect (DFG Nationallizenzen)

Beschreibungen/Notizen

• This is the first report of clastogenic effects of chlorinated hydroxyfuranones (CHFs) in plants. Two byproducts of water chlorination, 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5 H]-furanone (MX) and 3,4-dichloro 5-hydroxy-2[5 H]-furanone (MA) induced a dose dependent increase of micronuclei (MN) in pollen mother cells of Tradescantia when doses up to 100 μg MX and 500 μg MA were applied directly to the inflorescences. In contrast, exposure of the stems in aqueous solutions containing up to 1 mg/I MX and 10 mg/I MA did not cause a positive response.