Details

Autor(en) / Beteiligte

• FLEMING, T. E.
• MIRANDO, W. S.
• SOOHOO, L. F.
• COOPER, B. W.
• ZAIM, M. T.
• LAZARUS, H. M.
• ELMETS, C. A.

Titel

An inflammatory eruption associated with recombinant human IL-6

Ist Teil von

• British journal of dermatology (1951), 1994-04, Vol.130 (4), p.534-536

Ort / Verlag

Oxford, UK: Blackwell Publishing Ltd

Erscheinungsjahr

1994

Quelle

Wiley-Blackwell Journals

Beschreibungen/Notizen

• Summary Interleukin 6 (IL‐6) is an endogenous cytokine with multiple biological functions, including amplification of the inflammatory response. Recombinant human IL‐6, administered as part of a chemotherapeutic regimen, has recently been shown to cause regression of certain types of malignant tumours. We report a patient who developed a cutaneous eruption consisting of coalescent, erythematous, scaling macules and papules after administration of recombinant human IL‐6, given as part of her chemotherapy for ductal carcinoma of the breast.