Details

Autor(en) / Beteiligte

• Hioki, Ayana
• Masuda, Kasumi
• Asanuma, Toshihiko
• Goto, Yoichi
• Nakatani, Satoshi

Titel

Application of three-dimensional speckle tracking echocardiography to assess left ventricular regional work using wall tension-regional area loop

Ist Teil von

• American journal of physiology. Heart and circulatory physiology, 2015-05, Vol.308 (10), p.H1258-H1264

Ort / Verlag

United States: American Physiological Society

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• Three-dimensional (3-D) speckle tracking echocardiography allows us to track a change in regional endocardial surface area. The change of regional area during a cardiac cycle should be useful for assessing left ventricular regional work. We investigated the feasibility of assessing regional work, calculated as the area within the wall tension-regional area (T-A) loop using 3-D echocardiography. Three-dimensional full-volume images were acquired using 3-D echocardiography (Artida, Toshiba) at baseline and during brief occlusion of the left circumflex coronary artery in eight dogs. Wall tension was calculated according to Laplace's law for a spherical model. Area change ratio (in %) determined by area tracking was transformed into a change of regional area (in cm(2)) by a custom software. We calculated the area within the T-A loop (TAA) in the area under transient ischemia (risk area) and the remote area as regional work and validated the T-A loop method by comparing the global integral of TAA with the total work assessed by the pressure-volume loop. During coronary occlusion, regional work for the risk area significantly decreased (baseline vs. occlusion, 26.8 ± 10.7 vs. 18.4 ± 7.8 mmHg·cm(3); P < 0.05), whereas that for the remote area did not change. The global integral of TAA closely correlated with the total work assessed by the pressure-volume loop (r = 0.91, P < 0.0001). The wall T-A loop reflected regional dysfunction caused by myocardial ischemia. This analysis using 3-D speckle tracking echocardiography might be useful to quantify left ventricular regional work.