Oral oncology, 2015-06, Vol.51 (6), p.e57-e59
2015
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Details
- Autor(en) / Beteiligte
- Titel
- Extra-pulmonary small cell carcinoma in the head and neck setting: The role of prophylactic cranial irradiation
- Ist Teil von
- Oral oncology, 2015-06, Vol.51 (6), p.e57-e59
- Ort / Verlag
- England: Elsevier Ltd
- Erscheinungsjahr
- 2015
- Quelle
- Access via ScienceDirect (Elsevier)
- Beschreibungen/Notizen
- Summary Head-and-neck small cell carcinoma (HN-SmCC) is a rare entity and there is limited data to support management decisions. The role of prophylactic cranial irradiation (PCI) remains controversial. A retrospective review of 21 consecutive HN-SmCCs was performed. No case received PCI. The 2-year overall survival, local, regional and distant control rates were 65%, 94%, 88%, and 76% respectively. Despite no patient receiving PCI, brain metastases were uncommon ( n = 2) and routine use of PCI is not justified in this population.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1368-8375eISSN: 1879-0593DOI: 10.1016/j.oraloncology.2015.03.014Titel-ID: cdi_proquest_miscellaneous_1680956530
- Format
- –
- Schlagworte
- Adult, Aged, Aged, 80 and over, Brain metastases, Brain Neoplasms - secondary, Carcinoma, Small Cell - mortality, Carcinoma, Small Cell - secondary, Carcinoma, Small Cell - therapy, Chemoradiotherapy, Cranial Irradiation - utilization, Female, Head and neck carcinoma, Head and Neck Neoplasms - mortality, Head and Neck Neoplasms - pathology, Head and Neck Neoplasms - therapy, Hematology, Oncology and Palliative Medicine, Humans, IMRT, Local failure, Male, Middle Aged, Neurocognition, Otolaryngology, Patterns of failure, Prognosis, Prophylactic cranial irradiation, Retrospective Studies, Small cell carcinoma, Survival Rate, Whole brain radiation