Details

Autor(en) / Beteiligte

• Verma, Atul
• Jiang, Chen-yang
• Betts, Timothy R
• Chen, Jian
• Deisenhofer, Isabel
• Mantovan, Roberto
• Macle, Laurent
• Morillo, Carlos A
• Haverkamp, Wilhelm
• Weerasooriya, Rukshen
• Albenque, Jean-Paul
• Nardi, Stefano
• Menardi, Endrj
• Novak, Paul
• Sanders, Prashanthan

Titel

Approaches to Catheter Ablation for Persistent Atrial Fibrillation

Ist Teil von

• The New England journal of medicine, 2015-05, Vol.372 (19), p.1812-1822

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• In patients with persistent atrial fibrillation, rates of recurrent atrial fibrillation at 18 months were not significantly different when linear ablation or ablation of complex fractionated electrograms was performed along with pulmonary-vein isolation. Percutaneous catheter ablation is an effective treatment for paroxysmal atrial fibrillation, 1 – 3 particularly in cases that are refractory to antiarrhythmic medications. 4 – 6 Most triggers for paroxysmal atrial fibrillation come from the pulmonary veins, so ablation involves creating circumferential lesions around the veins to electrically isolate them from the rest of the left atrium. 7 Catheter ablation for persistent atrial fibrillation is more challenging and is associated with less favorable outcomes. 8 , 9 To improve outcomes, ablation targeting the substrate that maintains fibrillation (i.e., substrate modification) is often added to pulmonary-vein isolation. 10 , 11 The two most common techniques for substrate modification are the . . .