Journal of antimicrobial chemotherapy, 1994-12, Vol.34 (6), p.1025-1029
1994
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Details
- Autor(en) / Beteiligte
- Titel
- Additive effect of clarithromycin combined with 14-hydroxy clarithromycin, erythromycin, amoxycillin, metronidazole or omeprazole against Helicobacter pylori
- Ist Teil von
- Journal of antimicrobial chemotherapy, 1994-12, Vol.34 (6), p.1025-1029
- Ort / Verlag
- Oxford: Oxford University Press
- Erscheinungsjahr
- 1994
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The in-vitro activities of clarithromycin, 14-OH clarithromycin, erythromycin, amoxycillin, metronidazole and omeprazole against Helicobacter pylori were determined at pH 7.2 and 5.5. At pH 5.5 the activities of clarithromcycin and erythromycin decreased approximately 16 times while 14-OH clarithromycin was less influenced. Chequerboard titration indicated that the combined activity of clarithromycin and the other compounds was additive.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0305-7453eISSN: 1460-2091DOI: 10.1093/jac/34.6.1025Titel-ID: cdi_proquest_miscellaneous_16794614
- Format
- –
- Schlagworte
- Amoxicillin - pharmacology, Antibacterial agents, Antibiotics. Antiinfectious agents. Antiparasitic agents, Biological and medical sciences, Clarithromycin - analogs & derivatives, Clarithromycin - metabolism, Clarithromycin - pharmacology, Drug Synergism, Drug Therapy, Combination - pharmacology, Erythromycin - pharmacology, Helicobacter pylori, Helicobacter pylori - drug effects, Humans, Hydrogen-Ion Concentration, Medical sciences, Metronidazole - pharmacology, Microbial Sensitivity Tests, Omeprazole - pharmacology, Pharmacology. Drug treatments