Food chemistry, 2013-01, Vol.136 (1), p.259-265
2013
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- Autor(en) / Beteiligte
- Titel
- Hypocholesterolemic effects of low calorie structured lipids on rats and rabbits fed on normal and atherogenic diet
- Ist Teil von
- Food chemistry, 2013-01, Vol.136 (1), p.259-265
- Ort / Verlag
- Kidlington: Elsevier Ltd
- Erscheinungsjahr
- 2013
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- ► Two structured lipids (SLs) containing essential fatty acids were prepared. ► Calorific value of these two SLs is in the range of 5.2–5.4 Kcal/g. ► SLs have hypocholesterolemic effects on rats/rabbits, fed on normal/atherogenic diets. ► SLs reduce lipid accumulation in the arteries of rabbits given atherogenic diets. ► SLs will find applications in the food industry as low calorie fat substitute having hypocholesterolemic activity. The hypocholesterolemic effects of two low calorie structured lipids (SL1 and SL2) containing essential fatty acids, prepared by lipase catalysed interesterification of ethyl behenate respectively with sunflower and soybean oils were studied in rats and rabbits. The feeding experiment conducted on rats as well as rabbits, fed on normal and atherogenic diet containing 10% of SL1 and SL2 (experimental) and sunflower oil (control) indicated no adverse effects on growth and food intake. However, the structured lipids beneficially lowered serum and liver lipids, particularly cholesterol, LDL cholesterol, triglycerides and also maintains the essential fatty acid status in serum and liver. The lipid deposition observed in the arteries of rabbits fed on atherogenic diets was significantly reduced when structured lipids were included in the diet. These observations coincided with reduced levels of serum cholesterol particularly LDL cholesterol observed in experimental groups. Therefore the structured lipids, designed to have low calorific value also beneficially lower serum lipids and lipid deposition in animals fed on atherogenic diets.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0308-8146eISSN: 1873-7072DOI: 10.1016/j.foodchem.2012.07.116Titel-ID: cdi_proquest_miscellaneous_1671437517
- Format
- –
- Schlagworte
- adverse effects, Animals, Anticholesteremic Agents - chemistry, Anticholesteremic Agents - metabolism, Atherogenic diet, Behenic acid, Biological and medical sciences, blood lipids, cholesteremic effect, Cholesterol, Cholesterol - blood, Deposition, Diet, Atherogenic - adverse effects, Dietary Fats - analysis, Dietary Fats - metabolism, Diets, Essential fatty acids, Fat industries, Fatty acids, Feeding. Feeding behavior, feeds, Food industries, food intake, Fundamental and applied biological sciences. Psychology, Humans, Hypercholesterolemia - etiology, Hypercholesterolemia - metabolism, Hypercholesterolemia - prevention & control, Hypocholesterolemic activity, LDL cholesterol, Lipid Metabolism, Lipids, Low calorie fat, low density lipoprotein, Male, Plant Oils - chemistry, Plant Oils - metabolism, Rabbits, Rats, Rats, Wistar, Serums, Soybean Oil - chemistry, Soybean Oil - metabolism, Structured lipid, structured lipids, Sunflower Oil, Vertebrates: anatomy and physiology, studies on body, several organs or systems