Journal of dermatological science, 2015-04, Vol.78 (1), p.34-43
2015
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Human sebum extract induces barrier disruption and cytokine expression in murine epidermis
- Ist Teil von
- Journal of dermatological science, 2015-04, Vol.78 (1), p.34-43
- Ort / Verlag
- Netherlands: Elsevier Ireland Ltd
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • Sebum imparts detrimental effects on skin permeability barrier of hairless mice. • Skin barrier disruption by sebum elicits an epidermal inflammatory cascade. • Sebum-induced dermatitis resembles irritant contact dermatitis.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0923-1811eISSN: 1873-569XDOI: 10.1016/j.jdermsci.2015.01.010Titel-ID: cdi_proquest_miscellaneous_1669837088
- Format
- –
- Schlagworte
- Adult, Animals, Cytokine expression, Cytokines - immunology, Cytokines - metabolism, Dermatitis, Dermatitis, Irritant - immunology, Dermatitis, Irritant - metabolism, Dermatitis, Irritant - pathology, Dermatology, Epidermal barrier function, Epidermis - immunology, Epidermis - metabolism, Epidermis - pathology, Erythema - immunology, Erythema - metabolism, Erythema - pathology, Human sebum, Humans, Hyperplasia, Inflammation Mediators - immunology, Inflammation Mediators - metabolism, Male, Membrane Fluidity, Membrane Lipids - metabolism, Mice, Hairless, Morphology, Parakeratosis - immunology, Parakeratosis - metabolism, Parakeratosis - pathology, Permeability, Sebum - immunology, Sebum - metabolism, Time Factors, Water Loss, Insensible