Details

Autor(en) / Beteiligte

• Schommers, Philipp
• Hentrich, Marcus
• Hoffmann, Christian
• Gillor, Daniel
• Zoufaly, Alexander
• Jensen, Björn
• Bogner, Johannes R.
• Thoden, Jan
• Wasmuth, Jan‐Christian
• Wolf, Timo
• Oette, Mark
• Müller, Markus
• Esser, Stefan
• Vehreschild, Jörg J.
• Fätkenheuer, Gerd
• Wyen, Christoph

Titel

Survival of AIDS‐related diffuse large B‐cell lymphoma, Burkitt lymphoma, and plasmablastic lymphoma in the German HIV Lymphoma Cohort

Ist Teil von

• British journal of haematology, 2015-03, Vol.168 (6), p.806-810

Ort / Verlag

England

Erscheinungsjahr

2015

Link zum Volltext

Quelle

Wiley Online Library Journals Frontfile Complete

Beschreibungen/Notizen

• Summary Overall survival (OS) of patients with acquired immunodeficiency syndrome (AIDS)‐related Burkitt lymphoma (BL), diffuse large B‐cell lymphoma (DLBCL) and plasmablastic lymphoma (PBL) was analysed in the German AIDS‐related‐Lymphoma‐Cohort‐Study. Of 291 patients prospectively included between January 2005 and December 2012, 154 had DLBCL, 103 BL and 34 PBL. Two‐year OS rates were similar between BL (69%) and DLBCL patients (63%) but lower for PBL patients (43%). Intermediate (Hazard ratio [HR] 4·1 95% confidence interval [CI] 1·98–8·49) or high (HR 4·92 95% CI 2·1–11·61) International Prognostic Index, bone marrow involvement (HR 1·69 95% CI 1·00–2·84) and PBL histology (HR 2·24 95% CI 1·24–4·03) were independent predictors of mortality.