Neuroscience, 2015-02, Vol.286, p.364-370
2015
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Details
- Autor(en) / Beteiligte
- Titel
- Effect of prenatal exposure to LPS combined with pre- and post-natal high-fat diet on hippocampus in rat offspring
- Ist Teil von
- Neuroscience, 2015-02, Vol.286, p.364-370
- Ort / Verlag
- United States: Elsevier Ltd
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights • Prenatal LPS (0.4 mg/kg) results in pathological impairment in the hippocampus in offspring. • Prenatal exposure to high-fat diet results in systemic inflammation in offspring rats. • Prenatal LPS and high-fat diet result in protective effect on the hippocampus in offspring. • Predictive adaptive response may underlie the protective effect on the hippocampus.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0306-4522eISSN: 1873-7544DOI: 10.1016/j.neuroscience.2014.12.002Titel-ID: cdi_proquest_miscellaneous_1668245405
- Format
- –
- Schlagworte
- Animals, Diet, High-Fat - adverse effects, Female, Glial Fibrillary Acidic Protein - metabolism, high-fat diet/high cholesterol diet, hippocampus, Hippocampus - metabolism, inflammation, Inflammation - metabolism, Interleukin-6 - blood, lipopolysaccharide, Lipopolysaccharides - toxicity, Male, Neurology, Pregnancy, Prenatal Exposure Delayed Effects - metabolism, prenatal stress, Rats, Rats, Sprague-Dawley, Synaptophysin - metabolism, tau Proteins - metabolism, Tumor Necrosis Factor-alpha - blood