Details

Autor(en) / Beteiligte

• Gardien, Pauline
• Moineau, Marie-Pierre
• Kerspern, Hélène
• Bordron, Anne
• Carre, Jean-Luc

Titel

Comparative study of parathormone and vitamin D measurements by three automats: ADVIA Centaur XP® (Siemens), ISYS® (IDS) and Liaison® (Diasorin)

Ist Teil von

• Annales de biologie clinique (Paris), 2014-07, Vol.72 (4), p.443-452

Ort / Verlag

France

Erscheinungsjahr

2014

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• Vitamin D (Vit.D) and parathormone (PTH) measurements are usually prescribed for phosphocalcic metabolism assessment and, especially for Vit.D, more and more frequently for other pathologies. In order to step up to automated techniques for these analysis in our laboratory, we tested 3 devices: ADVIA Centaur XP(®) (Siemens), ISYS(®) (IDS) and Liaison(®) (Diasorin), which allow to simultaneously quantify Vit.D and PTH. The aim of this study was to evaluate the fidelity of these methods as well as study the correlation between them and the radioimmunological techniques previously used in our laboratory : « ELSA PTH » (Iba Cisbio International) and « 25-OH D » (IDS). The comparison of PTH analysis was performed on a population of chronic renal failure patients undergoing haemodialysis. According to our study, the 3 devices show acceptable analytical performances; anyway the measurements realized on the ISYS analyzer are the ones showing the best results in terms of fidelity, and the closest results to those obtained with the RIA reference techniques.