Details

Autor(en) / Beteiligte

• Heidt, Sebastiaan
• Eikmans, Michael
• Roelen, Dave L
• van Kooten, Cees
• Claas, Frans H.J

Titel

Immunogenetics and immunology of transplantation in Leiden

Ist Teil von

• Transplant immunology, 2014-10, Vol.31 (4), p.195-199

Ort / Verlag

Netherlands: Elsevier B.V

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• Abstract The historical observation of Jon van Rood that pregnancy can lead to the induction of HLA antibodies (1) was the start of a long history of research on immunogenetics and immunology of transplantation in Leiden. Some of the current research topics are presented in this mini-review. These include amongst others the differential immunogenicity of HLA mismatches in clinical transplantation, a special strategy to transplant highly sensitized patients, new tools to monitor donor specific memory B cells, new parameters for risk assessment in transplant recipients and the importance of the innate immune response in transplantation.