The Journal of infectious diseases, 2014-03, Vol.209 (5), p.734-738
2014
Details
- Autor(en) / Beteiligte
- Titel
- Clinical Factors That Predict Noncirrhotic Portal Hypertension in HIV-Infected Patients: A Proposed Diagnostic Algorithm
- Ist Teil von
- The Journal of infectious diseases, 2014-03, Vol.209 (5), p.734-738
- Ort / Verlag
- Oxford: Oxford University Press
- Erscheinungsjahr
- 2014
- Link zum Volltext
- Quelle
- Oxford Journals 2020 Medicine
- Beschreibungen/Notizen
- Noncirrhotic portal hypertension (NCPH) is a rare but important clinical entity in human immunodeficiency virus (HIV) populations. The purpose of this study was to describe the clinical factors associated with the condition in an effort to formulate a diagnostic algorithm for easy and early diagnosis. We performed a multicenter, retrospective case-control study of 34 patients with NCPH and 68 control HIV patients. The study found that thrombocytopenia, splenomegaly, didanosine use, elevated aminotransferases, and an elevated alkaline phosphatase level were all significantly more prevalent in the NCPH cohort. Using these easily available clinical parameters, we developed an algorithm for early diagnosis of NCPH in HIV.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0022-1899eISSN: 1537-6613DOI: 10.1093/infdis/jit412Titel-ID: cdi_proquest_miscellaneous_1654694136
- Format
- –
- Schlagworte
- Adult, Algorithms, Biological and medical sciences, Biopsies, Case-Control Studies, Female, Fibrosis, Fundamental and applied biological sciences. Psychology, HIV, HIV Infections - complications, HIV/AIDS, Human immunodeficiency virus, Human viral diseases, Humans, Hypertension, Portal - diagnosis, Infectious diseases, Liver, Liver diseases, Male, Medical sciences, Microbiology, Middle Aged, Phosphatases, Portal hypertension, Retrospective Studies, Splenomegaly, Statistical median, Tracheoesophageal fistula, Viral diseases, Viral diseases of the lymphoid tissue and the blood. Aids